gMG (Generalized Myasthenia Gravis)
Overview
Generalized Myasthenia Gravis (gMG) is a rare autoimmune disease of the nerves and muscles that leads to muscle weakness. For many people, gMG can cause symptoms of fatigue and muscle weakness that impair the muscles used for seeing, speaking, eating, walking, or using your arms and breathing.
In some people with gMG, immune proteins known as anti-acetylcholine (anti-AchR) antibodies disrupt nerve-to-muscle communication by activating complement, a part of the immune system that, in healthy bodies, helps fight bacteria and other threats. In some patients with gMG, the anti-AchR antibodies activate (or turn on) complement, causing disruptions to nerve-to-muscle communication.
Resources
MYASTHENIA GRAVIS FOUNDATION OF AMERICA (MGFA)
A national volunteer health agency that is dedicated solely to the fight against myasthenia gravis.
MUSCULAR DYSTROPHY ASSOCIATION (MDA)
Works to free patients and caregivers from the harm of muscular dystrophy, amyotrophic lateral sclerosis (ALS), and related muscle-debilitating diseases that take away physical strength, independence, and life.
GLOBAL GENES
One of the leading rare disease patient advocacy organizations in the world. This nonprofit organization promotes the needs of the rare disease community.
NATIONAL ORGANIZATION FOR RARE DISORDERS (NORD)
A unique group of organizations whose aim is to help people living with rare diseases. They provide advocacy, education, and other services to improve the lives of all people affected by rare diseases.
